nf-core/plasmodiumdrugres
Pipeline for analyzing drug resistance markers from Plasmodium microhaplotype data. Translates variants into amino acid changes at drug resistance loci and estimates allele frequencies and prevalences at both single-locus and multi-locus levels. Microhaplotype data can be supplied in the form of an allele table or a PMO file.
drug-resistancefrequency-estimationgenomicshaplotypesmulti-locusphasingplasmodiumplasmodium-falciparumpopulation-geneticsprevalence-estimation
Version history
What’s Changed
- Add PGEcore as a submodule by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/1
- Feature/add count samples by coi module by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/4
- Update PGEcore by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/6
- Adding dockerfile by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/5
- Updating Dockerfile for more R packages by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/10
- Feature/extract allele table by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/7
- Update pg ecore by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/18
- Feature/idm module by @a-hubbard in https://github.com/nf-core/plasmodiumdrugres/pull/15
- Feature/allele prev naive by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/13
- updated docker and PGEcore to remove devtools dependency; by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/21
- Feature/translate loci of interest by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/11
- adding pileup_specific_snps; by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/17
- Add module and tests for slaf_from_stave_mlaf.R by @a-hubbard in https://github.com/nf-core/plasmodiumdrugres/pull/19
- Rename IDM module emission from slaf_output to slaf by @a-hubbard in https://github.com/nf-core/plasmodiumdrugres/pull/22
- Feature/naive coi by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/16
- Rename IDM_wrapper.nf to idm_wrapper.nf by @a-hubbard in https://github.com/nf-core/plasmodiumdrugres/pull/25
- Update column names in allele table by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/26
- Feature/multilocus prev freq naive by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/24
- Feature/mlbm module by @a-hubbard in https://github.com/nf-core/plasmodiumdrugres/pull/23
- Feature/add allele freq naive by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/27
- fix md5sum check for mlbm by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/29
- added nextflow for extract ref_seqs via fasta or a genome; by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/28
- Feature/extract panel to bed by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/31
- Updating Dockerfile and PGEcore by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/33
- Feature/dcifer module by @a-hubbard in https://github.com/nf-core/plasmodiumdrugres/pull/30
- update PGEcore; update mlaf for new PGEcore function; updated md5sum … by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/35
- exposed a new MLBM argument for filtering low occurrence aa calls; by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/42
- Updating main drug resistance pipeline by @nickjhathaway in https://github.com/nf-core/plasmodiumdrugres/pull/44
- Feature/add main drug res workflow by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/39
- Feature/update pgecore version by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/47
- Hotfix/update aa table split by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/48
- Hotfix/update default methods by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/49
- Feature/generate population map from pmo by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/50
- update docs by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/51
- Feature/dockerhub deploy by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/53
- update author to PlasmoGenEpi for dockerfile by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/54
- Dev by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/55
- add instructions about cloning the repo by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/60
- Hotfix/add temporary nextflow note by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/66
- add instructions for pulling image with different platform and remove… by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/65
- Hotfix/docker failing build by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/71
- Update colours, tools, and structure of metro map by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/70
- Stop tracking .vscode and ignore i by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/74
- index population assignment and use this internally to remove issues … by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/73
- Hotfix/update test data by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/79
- update linting param intput by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/77
- Update to use the nf-core test repo data by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/80
- Feature/create conda environments by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/81
- Update syntax for nextflow 26 by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/82
- Template sync by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/84
- Update tool option handling and add subworkflow meta files by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/85
- Standardise outputs from tools by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/75
- allow no loci groups and ml won’t run by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/78
- Accurately represent current state in metromap; Update colours by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/88
- Hotfix/update env documentation by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/89
- bump pipeline version for release and update snapshots by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/86
- Add
manifest.diagramtonextflow.configby @ewels in https://github.com/nf-core/plasmodiumdrugres/pull/91 - Update pipeline to use new PGEcore R package by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/92
- Add date to change log; remove nf-core todo from conributing doc by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/93
- Add fem coi as a parameter that can be passed to the pipeline by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/95
- Hotfix/unnasigned specimens by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/94
- Use real surveillance data for test_full; set collapse to full; colla… by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/103
- Add white panel to metromap for darkmode by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/105
- Hotfix/tidy docs and modules by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/107
- Switch fix-linting to the hardened nf-core/actions reusable workflow by @mashehu in https://github.com/nf-core/plasmodiumdrugres/pull/111
- Hotfix/release blockers by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/112
- Update default branch to main by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/96
- Update date of release by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/114
- Dev by @kathrynmurie in https://github.com/nf-core/plasmodiumdrugres/pull/90
New Contributors
- @kathrynmurie made their first contribution in https://github.com/nf-core/plasmodiumdrugres/pull/1
- @nickjhathaway made their first contribution in https://github.com/nf-core/plasmodiumdrugres/pull/10
- @a-hubbard made their first contribution in https://github.com/nf-core/plasmodiumdrugres/pull/15
- @ewels made their first contribution in https://github.com/nf-core/plasmodiumdrugres/pull/91
- @mashehu made their first contribution in https://github.com/nf-core/plasmodiumdrugres/pull/111
Full Changelog: https://github.com/nf-core/plasmodiumdrugres/commits/1.0.0